Rebekah Carrington is a master violinist trained in Vienna who works her way into an audition with the newly formed Nashville Philharmonic. There is a growing consencus that women are "far too fragile and frail" for the demands and challenges of the orchestra. Rebekah's hopes hit a low note when the conductor is easily influenced by public opinion. To top it off, Adelicia Acklen Cheatham, mistress of Belmont Mansion and Rebekah's new employer, sides with the conductor.
Nathaniel Tate Whitcomb, nationally acclaimed conductor, is Nashville's new orchestra leader. He is compelled to finish his symphony before the grand opening of the city's new opera hall, but he faces obstacles of a reluctant muse and a bizarre buzzing pain in his head. He also wants to share the symphony with his dying father, who first inspired his love of music. As his condition worsens, he believes Rebekah may be able to help him finish his symphony. But how can he harmonize with a woman after he laid her dreams to rest?